Cultivation of sensitivity to reverse translational research through pharmacy education

Author: Masato Yasuhara

Category: Pharmacy

Abstract:

Reverse translational research begins with actual, real-life patient experiences in the clinic and works backward to uncover the mechanistic basis for these clinical observations. The goal of reverse translational research is to generate actionable hypotheses about disease mechanisms and drug response supporting validation of existing targets, identifying new targets and disease mechanisms/indications, and driving precision medicine strategies. A report from Science Council of Japan pointed out that reverse translational research is a promising way to promote the science and practice of clinical pharmacy. The revised model core curriculum for pharmacy education in Japan proposed 10 professional competencies for pharmacists. Research is included in 10 competencies. By conducting research in the undergraduate course, students will develop the ability to use knowledge and skills comprehensively and to solve problems through research processes. Fostering a pharmacist with a research mind is expected to contribute to advancement of reverse translational research through detection of clinical problems and accumulation of objective information.

Keywords: reverse translational research, pharmacy education, core curriculum, clinical pharmacy