JOURNAL OF ASIAN ASSOCIATION OF SCHOOLS OF PHARMACY - Volume 10, January - December, 2021

Pages: 1-8
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Sulfur-containing compounds from leaves of Allium plants, A. fistulosum, A. schoenoprasum var. foliosum, and A. sativum

Author: Seikou Nakamura, Souichi Nakashima, Hisashi Matsuda

Category: Pharmacy

Abstract:

Allium plants are known worldwide as medicinal foodstuffs. A number of sulfur-containing compounds have been isolated from Allium plants, including allicin and ajoene, which are known for their biofunctional activities, such as anticancer activity. In the course of studies of sulfur-containing compounds, sulfur-containing multiple-ring compounds and thiolanetype compounds were isolated from the leaves of Allium fistulosum, Allium schoenoprasum var. foliosum, and Allium sativum. The chemical structures of these compounds were elucidated on the basis of physicochemical evidence. In addition, the biosynthetic pathways for these compounds were proposed. In this paper, studies on sulfur-containing compounds from the leaves and the whole plants of A. fistulosum ‘kujou’, A. schoenoprasum var. foliosum, and A. sativum and their proposed biosynthetic pathways are reviewed.

Keywords: Allium fistulosum, Allium schoenoprasum var. foliosum, Allium sativum, sulfur-containing compound, tetrahydrothiophene