JOURNAL OF ASIAN ASSOCIATION OF SCHOOLS OF PHARMACY - Volume 13 Issue 1, January - December 2024

Pages: 40-46

Date of Publication: 27-Dec-2024

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Utilization of intravenous proton pump inhibitors in non-critically ill patients and the impact of pharmacist-led interventions in a private tertiary hospital in Metro Manila, Philippines

Author: Sofia M. Cortez, Imelda G. Peña* , Yolanda R. Robles, Vina Rose D. Talan, Francis R. Capule, Hazel Faye R. Docuyanan

Category: Pharmacy

Abstract:

Objectives: The study aims to evaluate the impact of pharmacist-led interventions on the utilization of intravenous proton pump inhibitors (IV PPIs). Methods: A two-phase study with quasi-experimental design compared outcomes relevant to inappropriate IV-PPI utilization before and after implementation of pharmacist-led interventions through retrospective review of dispensing records of 508 patients admitted to different wards of a private tertiary hospital in the Philippines. Pharmacist-led interventions include creation of institution-specific guidelines on appropriate IV PPI therapy and educational interventions for prescribers. Results: The interventions contributed to 4.4% decrease in prescribed IV PPI, 28.5% decrease in inappropriate IV PPI orders and 23.7% and 25.3% decrease in the cost of inappropriate use of Omeprazole and Pantoprazole, respectively. Conclusion: Reductions in the prescribing rate of IV PPI, inappropriate IV PPI orders and cost of inappropriate therapy after implementing pharmacist interventions, supported the need for continuous education of physicians on appropriate IV PPI therapy.

Keywords: Proton pump inhibitors, pharmacists, Omeprazole, Pantoprazole

DOI URL: https://doi.org/10.62100/jaasp.2024.13106