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  <Article>
    <Journal>
      <PublisherName>aaspjournal</PublisherName>
      <JournalTitle>Journal of Asian Association of Schools of Pharmacy</JournalTitle>
      <PISSN>I</PISSN>
      <EISSN>S</EISSN>
      <Volume-Issue>Volume 1 No.3</Volume-Issue>
      <PartNumber/>
      <IssueTopic>Multidisciplinary</IssueTopic>
      <IssueLanguage>English</IssueLanguage>
      <Season>July - September, 2012</Season>
      <SpecialIssue>N</SpecialIssue>
      <SupplementaryIssue>N</SupplementaryIssue>
      <IssueOA>Y</IssueOA>
      <PubDate>
        <Year>-0001</Year>
        <Month>11</Month>
        <Day>30</Day>
      </PubDate>
      <ArticleType>Pharmacy</ArticleType>
      <ArticleTitle>Analgesic, anti-inflammatory, antipyretic activities and acute toxicity of the ethanolic extract of Clausena harmandiana Pierre in animals</ArticleTitle>
      <SubTitle/>
      <ArticleLanguage>English</ArticleLanguage>
      <ArticleOA>Y</ArticleOA>
      <FirstPage>159</FirstPage>
      <LastPage>169</LastPage>
      <AuthorList>
        <Author>
          <FirstName>Jinda</FirstName>
          <LastName>Wangboonskul</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>N</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Auemduan</FirstName>
          <LastName>Prawan</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Pobporn</FirstName>
          <LastName>Takthaisong</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Watikan</FirstName>
          <LastName>Sasithornwetchakun</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Chantana</FirstName>
          <LastName>Boonyarat</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Chavi</FirstName>
          <LastName>Yenjai</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Pramote</FirstName>
          <LastName>Mahakunakorn</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
        </Author>
      </AuthorList>
      <DOI/>
      <Abstract>Clausena harmandiana Pierre (CH), a local plant used traditionally for pain relief and antipyretic, was used to investigate analgesic, anti-inflammatory, antipyretic activities and acute toxicity from an ethanolic extract of its root bark (CH-EtOH). Chemical analysis by HPLC indicated dentatin and nordentatin contents in CH-EtOH at 1.71 and 2.57% w/w, respectively. Analgesic activity of oral CH-EtOH was tested in mice by thermal threshold tests and acetic acid (AA)-induced writhing response, antiinflammatory by carrageenan-induced rat paw edema, antipyretic by baker yeast-induced fever rat model and acute toxicity followed OECD Guidelines. Oral CH-EtOH significantly decreased writhing responses in a dose-dependent manner (p</Abstract>
      <AbstractLanguage>English</AbstractLanguage>
      <Keywords>Clausena harmandiana analgesic anti-inflammatory antipyretic acute toxicity folk medicine</Keywords>
      <URLs>
        <Abstract>https://aaspjournal.org/ubijournal-v1copy/journals/abstract.php?article_id=5950&amp;title=Analgesic, anti-inflammatory, antipyretic activities and acute toxicity of the ethanolic extract of Clausena harmandiana Pierre in animals</Abstract>
      </URLs>
      <References>
        <ReferencesarticleTitle>References</ReferencesarticleTitle>
        <ReferencesfirstPage>16</ReferencesfirstPage>
        <ReferenceslastPage>19</ReferenceslastPage>
        <References/>
      </References>
    </Journal>
  </Article>
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