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Hypolipidemic Effect of the Lyophilized Fruit Pulp of Guyabano, Annona Muricata Linn. (Fam. Annonaceae) in Atherogenic Diet-Induced Hyperlipidemia in Albino Rats
de La Cruz Angelica May A, Catabay Alice P
The hypolipidemic activity of the three doses of lyophilized fruit pulp of Guyabano were evaluated in atherogenic diet-induced albino rats. Pre-test post-test experimental design was conducted by comparing the TC, TG, LDL-c, HDL-c, and AIP. Bioassay findings show that, the Guyabano fruit pulp can control, in a dose-dependent manner, the increase in TC, TG, LDL-c, AIP, and decrease in HDL-c caused by high fat and high cholesterol diet. Histopathological analysis of the liver, heart, and blood vessels also revealed that the fruit pulp was effective in curtailing the deposition of fats, implying its potential ability to prevent the occurrence of hyperlipidemia. Phytochemical screening confirmed that the fruit pulp contained condensed tannins, polyphenols, reducing sugars, fixed oils, proteins, saponins, unsaturated steroids, 2-deoxysugars and flavonoids potentially responsible for its hypolipidemic property.
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Other in Vol. 5 No. 1
Working With Older People - A Rich Learning Opportunity for Pharmacists
Factors Influencing Prescribing of Statins in Singapore Compared to Queensland, Australia
The Prescribing Pattern of Proton Pump Inhibitors by Non-gastroenterologists in a Tertiary Teaching Hospital in the Kingdom of Saudi Arabia
Formulation of Hand Sanitizer Gel using the Semi-Purified Flavonoids from the outer coverings of the Red Creole variety of Allium cepa Linn.: A preliminary investigation
Hypolipidemic Effect of the Lyophilized Fruit Pulp of Guyabano, Annona Muricata Linn. (Fam. Annonaceae) in Atherogenic Diet-Induced Hyperlipidemia in Albino Rats
Formulation and Characterization of Polyherbal Cream for Skin Manifestations
Effectiveness of Junior Faculty Mentoring Relationships in the Colleges of Pharmacy in Metro Manila, Philippines
Student Perceptions on Factors Affecting Academic Performance in a Tertiary Institution in Manila, Philippines
Philippine Pharmacists Licensure Examination (PPLE) Score Indicators: A Cebu School Experience
 
 


 
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