The Official Journal of Asian Association of Schools of Pharmacy
 
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In vitro uterine relaxant activity of Fire Ha Kong Recipe in rats
Penchom Peungvicha*, Yuvadee Wongkrajang, Boontium Kongsaktrakoon, Kanjana Jittiporn and Somsak Nualkaew
Fire Ha Kong recipe in a concentration range of 10-40 µl/ml was used to test in an in vitro uterine contraction inhibition. Contraction frequencies and amplitudes of the normal uterine of estrogen-primed non-pregnant rats were monitored. A decline in the frequencies of uterine contractions of 43.8 - 93.6% was detected. Addition of Fire Ha Kong at the final concentrations of 20-40 ?l/ml inhibited the amplitudes of uterus contraction by 57.1% and 85.7%, respectively. The reductions in area under the curve (AUC) of contractions were 57.1% and 85.7% for the added concentrations. Fire Ha Kong recipe revealed inhibitory effects on the uterine response to oxytocin (10-11 M) 31.9% and 29.3% only in frequency but not in amplitude and AUC in comparison to oxytocin alone. These results indicate that the tocolytic potential of Fire Ha Kong recipe may involve oxytocin receptor-dependent pathway or reduce the intracellular availability of calcium ions.
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Other in Vol. 3
Potential risks and hazards from herbal uses
Phylogenetic analysis of mcrA gene of methanogenic archaea
In vitro uterine relaxant activity of Fire Ha Kong Recipe in rats
Topical anti-inflammatory of a gel containing combined natural extracts
In vitro and in vivo skin whitening and anti-aging potentials of hydroglycolic extract from inflorescence of Etlingera elatior
Quality evaluation of purple waxy corn cobs for health use
 
 


 
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